2500-1800 BC In Northern Peru a remarkable finding of traces of Coca leaves in the area of the ruins of Huanca Prieto.
2100 BC In Valdivian culture of Ecuador and in ceramics of Nazca and Mochica cultures in Peru (600-360 BC) relevant findings of traditional use of Coca.
1200-1475 A kind of oils essence extracted from Coca leaves was used by Incas, when practising surgical excision of brain tumors.
The volume XVIII No 4, October-December 1978 of América Indígena is a monographic compilation of articles by different authors on the subject of Andean Coca, I was lucky enough to get one sample; the following scientific references are taken from the chapter A new perspective on the chewing of coca, written by Roderick E. Burchard of the Department of Anthropology of the University of Manitoba (Winnipeg, Canada); it is confirmed that the functional model of isolated cocaine alkaloid was assumed as a functional model of Coca in its entirety and that such a model for a long time had no alternatives.
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